Autoantibodies in pulmonary tuberculosis and leprosy in black South Africans

Show simple item record Rapoport, B. L. 2018-10-12T07:22:34Z 2018-10-12T07:22:34Z 1988-12-01
dc.description A dissertation submitted to the Faculty of Medicine, University of the Witwatersrand, Johannesburg, in fulfilment of the requirements for the Degree of Master of Medicine. J o h a n n e s b u r g 1988 en_ZA
dc.description.abstract Infections can cause autoantibody production. The purpose of this study was to determine the prevalence of autoantibodies in chronic mycobacterial infections in Johannesburg. Sera from 41 leprosy patients and from 49 untreated and 73 treated tuberculosis patients were tested for rheumatoid factor, antibodies against a panel of nuclear antigens, anticardiolipin antibodies and syphilis serology. The antinuclear antibody was positive in 7.3% of the leprosy group, 6.1% of the untreated TB group and 15% of the treated tuberculosis patients (p=0.0125). Antinuclear antibody positivity correlated with duration of treatment (p=0.025). The antinuclear antibody titres were low and there was no specific pattern. en_ZA
dc.language.iso en en_ZA
dc.subject.mesh Autoantibodies
dc.subject.mesh Tuberculosis, Pulmonary
dc.subject.mesh Leprosy
dc.subject.mesh Tuberculosis
dc.title Autoantibodies in pulmonary tuberculosis and leprosy in black South Africans en_ZA
dc.type Thesis en_ZA
dc.description.librarian IT2018 en_ZA

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