Clinical Medicine: Recent submissions

Now showing items 1-20 of 22

Serum Metabolomic and Lipoprotein Profiling of Pancreatic Ductal Adenocarcinoma Patients of African Ancestry

Elebo, Nnenna; Fru, Pascaline N.; Candy, Geoffrey; Nweke, Ekene (MDPI, 2021)

Pancreatic ductal adenocarcinoma (PDAC) is a lethal cancer with a characteristic dysregulated metabolism. Abnormal clinicopathological features linked to defective metabolic and inflammatory response pathways can induce ...
Sexual history taking: perspectives on doctor-patient interactions during routine consultations in rural primary care in South Africa

Pretorius, Deidre; Couper, Ian; Mlambo, Motlatso (Elsevier Inc., 2021-05-03)

Background: Sexual history taking for risk behavior contributes to improving health outcomes in primary care. Giving the high numbers of people living with AIDS, every patient in South Africa should be offered an HIV test, ...
Sexual history taking: doctors’ clinical decision-making in primary care in the North West province, South Africa

Pretorius, Deidre; Couper, Ian D; Mlambo, Motlatso G. (AOSIS, 2021-09-29)

Background: Clinical reasoning is an important aspect of making a diagnosis for providing patient care. Sexual dysfunction can be as a result of cardiovascular or neurological complications of patients with chronic illness, ...
Neglected sexual dysfunction symptoms amongst chronic patients during routine consultations in rural clinics in the North West province

Pretorius, Deidre; Couper, Ian D; Mlambo, Motlatso G. (AOSIS, 2021-04-28)

Background: Sexual dysfunction contributes to personal feelings of loss and despair and being a cause of exacerbated interpersonal conflict. Erectile dysfunction is also an early biomarker of cardiovascular disease. As ...
A radiation dose review for paediatric fluoroscopy in an Academic South African referral hospital

Venter, Mauritz (University of the of Witwatersrand, 2017)

INTRODUCTION Children are more sensitive to radiation and it is therefore important to reduce their exposure. There are currently no published data on South African paediatric fluoroscopic upper GIT, contrasted enemas and ...
HIV-related knowledge, perceptions, attitudes, and utilisation of HIV counselling and testing: a venue-based intercept commuter population survey in the inner city of Johannesburg, South Africa

Chimoyi, L; Tshuma, N; Muloongo, K; et al (2015)

Background: HIV counselling and testing (HCT) and knowledge about HIV have been key strategies utilised in the prevention and control of HIV/AIDS worldwide. HIV knowledge and uptake of HCT services in sub-Saharan Africa ...
Health-seeking behaviours by gender among adolescents in Soweto, South Africa

Otwombe, K.; Dietrich, J.; Laher, F.; et al (2015)

BACKGROUND: Adolescents are an important age-group for preventing disease and supporting health yet little is known about their health-seeking behaviours. OBJECTIVE: We describe socio-demographic characteristics and ...
Factors associated with mortality in HIV-infected people in rural and urban South Africa

Otwombe, K N; Petzold, M; Modisenyane, T; et al (2014)

Background: Factors associated with mortality in HIV-infected people in sub-Saharan Africa are widely reported. However rural urban disparities and their association with all-cause mortality remain unclear. Furthermore, ...
The cost of harmful alcohol use in South Africa

Matzopoulos, R G; Truen, S; Bowman, B; et al. (2014-02)

Background. The economic, social and health costs associated with alcohol-related harms are important measures with which to inform alcohol management policies and laws. This analysis builds on previous cost estimates for ...
National expenditure on health research in South Africa : What is the benchmark ?

Paruk, F.; Blackburn, J.M.; Friedman, I.B.; et al. (2014-07)

The Mexico (2004), Bamako (2008) and Algiers (2008) declarations committed the South African (SA) Ministry of Health to allocate 2% of the national health budget to research, while the National Health Research Policy (2001) ...
Rheumatic fever and rheumatic heart disease in Gauteng on the decline : Experience at Chris Hani Baragwanath Academic Hospital, Johannesburg. South Africa

Celliers, A M (2014-09)

Background: The incidence of rheumatic fever (RF) and its complications has waned over the past three to four decades throughout the Western world, but RF remains a problem in developing countries and in the indigenous ...
Setting ART initiation targets in response to changing guidelines : The importance of addressing both steady-state and backlog

Martin, C; Naidoo, N P; Venter, W D F; et al. (2014-06)

Background: Target setting is useful in planning, assessing and improving antiretroviral treatment (ART) programmes. In the past 4 years, the ART initiation environment has been transformed due to the change in eligibility ...
South African Menopause Society revised consensus position statement on menopausal hormone therapy, 2014

Guidozzi, F; Alperstein, A; Bagratee, J S; et al. (2014-08)

The South African Menopause Society (SAMS) consensus position statement on menopausal hormone therapy (HT) 2014 is a revision of the SAMS Council consensus statement on menopausal HT published in the SAMJ in May 2007. ...
The challenges of managing breast cancer in the developing world- a perspective from sub- Saharan Africa

Edge, J; Buccimazza, I; Cubasch, H; et al. (2014-05)

Communicable diseases are the major cause of mortality in lower-income countries. Consequently, local and international resources are channelled mainly into addressing the impact of these conditions. HIV, however, is being ...
Clinical access to Bedaquiline Programme for the treatment of drug-resistant tuberculosis

Conradie, F; Meintjies, G; Hughes, J; et al (2014-03)

While clinical disease caused by drug-sensitive Mycobacterium tuberculosis (MTB) can usually be treated successfully, clinical disease caused by drug-insensitive MTB is associated with a poorer prognosis. In December 2012, ...
Charting the path along the continuum of PMCT or HIV-1 to elimination and finally to eradication

Editorial (2014-01)

In this editorial we traverse the continuum of transmission of HIV-1 from mothers to children to highlight the biomedical history of this problem. Treatment has progressed from prevention with antiretrovirals (ARVs) through ...
New imaging approaches for improving diagnosis of childhood tuberculosis

Bélard, S; Andronikou, S; Pillay, T; et al (2014-03)
Prevalence and incidence of symmetrical symptomatic peripheral neuropathy in patients with multidrug - resistant TB

Conradie, F; Mabiletsa, T; Sefoka, M; et al (2014-01)

Background: Symptomatic symmetrical peripheral neuropathy (SSPN) is common in patients with HIV infection. It is also a common adverse event associated with both tuberculosis (TB) treatment and antiretroviral therapy (ART), ...
Self- induction of abortion among women accessing second- trimester abortion services in the public sector, Western Cape Province, South Africa : An exploratory study

Constant, D; Grossman, D; Lince, N; et al (2014-04)

Background: Despite South Africa's liberal abortion law permitting abortion on request in the first trimester and under restricted conditions for second-trimester pregnancies, the practice of unsafe self-induced abortion ...
Should HIV be a notifiable disease? Old questions with some new arguments

Venter, W D F; Black, A; Allais, L; et al (2014-09)

HIV notification enters national debate regularly, often introduced by politicians and supported by many individual healthcare workers. We argue that its proponents advance confused or poorly informed rationales for making ...

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Clinical Medicine: Recent submissions

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