The role of mononuclear cells in tuberculosis

Show simple item record Sussman, Garth 2018-10-17T12:52:02Z 2018-10-17T12:52:02Z 1992-06-03
dc.description Thesis presented in fulfilment of the requirements governing the degree of Philosophy in the School of Medicine, University of the Witwatersrand. Johannesburg en_ZA
dc.description.abstract Sonicates derived from Mycobacterium tuberculosis suppressed lymphocytes proliferation. Pulsing of monocytes with mycobacterial sonicates resulted in the release of high molecular weight lipids. Both these lipids and those prepared by column fractionation of mycobacterial sonicates suppressed lymphocyte blastogenesis.This effect was due to the activation and not the proliferation of CD8+ lymphocytes by the lipid containing mycobacterial fractions of Mr>200kDa that could be obtained in vitro by column fractions. en_ZA
dc.language.iso en en_ZA
dc.subject.mesh Cells
dc.subject.mesh Tuberculosis
dc.subject.mesh Mycobacterium tuberculosis
dc.subject.mesh CD8-Positive T-Lymphocytes
dc.title The role of mononuclear cells in tuberculosis en_ZA
dc.type Thesis en_ZA
dc.description.librarian IT2018 en_ZA

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